Diabetic foot ulcers in 60 participants were measured with imitoMeasure at 2, 4, 8, and 12 weeks post-therapy. The authors showed that the percentage reduction in wound size was greater in the group that received injected platelet-rich plasma (PRP) than in the group that received topical PRP treatment.
Although the role of PRP in diabetic foot ulcer healing is well established, the most effective route of administration has yet to be defined. The 2 groups were treated with freshly prepared autologous PRP, administered either perilesionally by injection or topically, once a week for 4 weeks.